What is the importance of biopsy in skin diseases?

As dermatologists, our examination methods include inspection (visual examination), palpation (manual examination of tissue), and in challenging cases, skin biopsy. We often receive photos from friends and family asking for a diagnosis based on the image.

While we can diagnose many cases from photos, seeing the patient and the lesion in person allows us to assess the total body distribution and the hardness or softness of the lesion, which is crucial for diagnosis. Dermoscopic examination, which magnifies the lesion, also helps us make a more accurate diagnosis.

So, if a skin biopsy is recommended to you, should you be worried?

Of course, the answer is no. Many dermatological diseases resemble each other in appearance. Even with a close examination, diagnoses may become confused if the lesion has persisted for a long time. In such cases, a biopsy may be necessary.

There are also situations where a biopsy is mandatory. In conditions such as psoriasis (scaly patches), pemphigus, vasculitis (inflammation of blood vessels), etc., where long-term medication is required, even if the diagnosis is clear, it may be necessary to confirm it with a biopsy. Additionally, biopsies are important when there are suspicious moles or cases suggestive of skin cancer.

In summary, a skin biopsy is helpful and necessary in many situations. After pathological examination, your doctor will determine the treatment and initiate the most accurate diagnosis-treatment process for you.